7JU3

MtrR bound to the mtrCDE operator from Neisseria gonorrhoeae

Summary for 7JU3

• Entry DOI: 10.2210/pdb7ju3/pdb
• Related: 7JNP
• Descriptor: HTH-type transcriptional regulator MtrR, DNA (5'-D(*TP*AP*TP*CP*CP*GP*TP*GP*CP*AP*AP*TP*CP*GP*TP*GP*TP*AP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*TP*AP*CP*AP*CP*GP*AP*TP*TP*GP*CP*AP*CP*GP*GP*AP*TP*A)-3'), ... (5 entities in total)
• Functional Keywords: tetr family, transcription, global regulator, helix-turn-helix motif, dna binding protein
• Biological source: Neisseria gonorrhoeae; More
• Total number of polymer chains: 4
• Total formula weight: 62048.66

Authors

Beggs, G.A.,Shafer, W.M.,Brennan, R.G. (deposition date: 2020-08-19, release date: 2021-03-24, Last modification date: 2023-10-18)

• Primary citation: Beggs, G.A.,Ayala, J.C.,Kavanaugh, L.G.,Read, T.D.,Hooks, G.M.,Schumacher, M.A.,Shafer, W.M.,Brennan, R.G.; Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations.; Nucleic Acids Res., 49:4155-4170, 2021; PubMed: 33784401; DOI: 10.1093/nar/gkab213

Experimental method

X-RAY DIFFRACTION (2.7 Å)