7JPS

ORC-DNA: Human Origin Recognition Complex (ORC) with DNA bound in the core

Summary for 7JPS

• Entry DOI: 10.2210/pdb7jps/pdb
• EMDB information: 22421
• Descriptor: Origin recognition complex subunit 1, POTASSIUM ION, Origin recognition complex subunit 2, ... (10 entities in total)
• Functional Keywords: replication, aaa+, orc, dna-binding, cryoem, replication-dna complex, replication/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 7
• Total formula weight: 303173.43

Authors

Jaremko, M.J.,Joshua-Tor, L. (deposition date: 2020-08-09, release date: 2020-09-09, Last modification date: 2022-10-26)

• Primary citation: Jaremko, M.J.,On, K.F.,Thomas, D.R.,Stillman, B.,Joshua-Tor, L.; The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.; Elife, 9:-, 2020; PubMed: 32808929; DOI: 10.7554/eLife.58622

Experimental method

ELECTRON MICROSCOPY (4.4 Å)