7JJC

Crystal structure of neuropilin-1 b1 domain in complex with SARS-CoV-2 S1 C-end rule (CendR) peptide

Summary for 7JJC

Entry DOI	10.2210/pdb7jjc/pdb
Descriptor	Neuropilin-1, Spike protein S1, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywords	neuropilin-1, receptor binding, coronavirus, sars-cov-2, spike protein, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	79201.25
Authors	Chen, K.-E.,Collins, B.M. (deposition date: 2020-07-25, release date: 2020-10-28, Last modification date: 2023-10-18)
Primary citation	Daly, J.L.,Simonetti, B.,Klein, K.,Chen, K.E.,Williamson, M.K.,Anton-Plagaro, C.,Shoemark, D.K.,Simon-Gracia, L.,Bauer, M.,Hollandi, R.,Greber, U.F.,Horvath, P.,Sessions, R.B.,Helenius, A.,Hiscox, J.A.,Teesalu, T.,Matthews, D.A.,Davidson, A.D.,Collins, B.M.,Cullen, P.J.,Yamauchi, Y. Neuropilin-1 is a host factor for SARS-CoV-2 infection. Science, 370:861-865, 2020 Cited by PubMed: 33082294 DOI: 10.1126/science.abd3072 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.36 Å)

Structure validation