7H3Q

Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with Z104924088 (A71EV2A-x0469)

This is a non-PDB format compatible entry.

Summary for 7H3Q

• Entry DOI: 10.2210/pdb7h3q/pdb
• Group deposition: Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease (G_1002288)
• Descriptor: Protease 2A, 2-[4-(propan-2-yl)piperazin-1-yl]pyrimidine, ZINC ION, ... (6 entities in total)
• Functional Keywords: diamond light source, i03, asap, coxsackievirus a16, crystallographic fragment screening, pandda, pandda2, xchemexplorer, viral protein, hydrolase
• Biological source: Coxsackievirus A16; More
• Total number of polymer chains: 1
• Total formula weight: 17269.67

Authors

Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Fearon, D.,von Delft, F. (deposition date: 2024-04-04, release date: 2024-04-24)

• Primary citation: Lithgo, R.M.,Fairhead, M.,Koekemoer, L.,Balcomb, B.H.,Capkin, E.,Chandran, A.V.,Golding, M.,Godoy, A.S.,Aschenbrenner, J.C.,Marples, P.G.,Ni, X.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Xavier, M.-A.E.,Fearon, D.,von Delft, F.; Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.05 Å)