7FJH

LecA from Pseudomonas aeruginosa in complex with 4-Phenylbutyryl hydroxamic acid (CAS: 32153-46-1)

Summary for 7FJH

Entry DOI	10.2210/pdb7fjh/pdb
Descriptor	PA-I galactophilic lectin, N-oxidanyl-4-phenyl-butanamide, CALCIUM ION, ... (4 entities in total)
Functional Keywords	calcium-binding lectins, glycomimetics, sugar binding protein
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	4
Total formula weight	51599.29
Authors	Shanina, S.,Kuhaudomlarp, S.,Siebs, E.,Fuchsberger, F.,Denis, M.,da Silva Figueiredo Celstino Gomes, P.,Clausen, M.H.,Seeberger, P.H.,Rognan, D.,Titz, A.,Imberty, A.,Rademacher, C. (deposition date: 2021-08-04, release date: 2022-06-08, Last modification date: 2023-11-29)
Primary citation	Shanina, E.,Kuhaudomlarp, S.,Siebs, E.,Fuchsberger, F.F.,Denis, M.,da Silva Figueiredo Celestino Gomes, P.,Clausen, M.H.,Seeberger, P.H.,Rognan, D.,Titz, A.,Imberty, A.,Rademacher, C. Targeting undruggable carbohydrate recognition sites through focused fragment library design. Commun Chem, 5:64-64, 2022 Cited by PubMed: 36697615 DOI: 10.1038/s42004-022-00679-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation