7FIG

luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex

Summary for 7FIG

• Entry DOI: 10.2210/pdb7fig/pdb
• EMDB information: 31596
• Descriptor: Engineered guanine nucleotide-binding protein G(s) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• Functional Keywords: glycoprotein hormone receptor, luteinizing hormone, chorionic gonadotropin, gpcr, gs-protein, membrane protein
• Biological source: Bos taurus (Bovine); More
• Total number of polymer chains: 7
• Total formula weight: 213676.94

Authors

Duan, J.,Xu, P.,Cheng, X.,Mao, C.,Croll, T.,He, X.,Shi, J.,Luan, X.,Yin, W.,You, E.,Liu, Q.,Zhang, S.,Jiang, H.,Zhang, Y.,Jiang, Y.,Xu, H.E. (deposition date: 2021-07-31, release date: 2021-09-29, Last modification date: 2022-02-16)

• Primary citation: Duan, J.,Xu, P.,Cheng, X.,Mao, C.,Croll, T.,He, X.,Shi, J.,Luan, X.,Yin, W.,You, E.,Liu, Q.,Zhang, S.,Jiang, H.,Zhang, Y.,Jiang, Y.,Xu, H.E.; Structures of full-length glycoprotein hormone receptor signalling complexes.; Nature, 598:688-692, 2021; PubMed: 34552239; DOI: 10.1038/s41586-021-03924-2

Experimental method

ELECTRON MICROSCOPY (3.9 Å)