7F0B

Crystal structure of capreomycin phosphotransferase in complex with ATP

Summary for 7F0B

Entry DOI	10.2210/pdb7f0b/pdb
Descriptor	Capreomycin phosphotransferase, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	cph, phosphotransferase, capreomycin, resistance, transferase
Biological source	Saccharothrix mutabilis subsp. capreolus (Streptomyces capreolus)
Total number of polymer chains	1
Total formula weight	31943.64
Authors	Chang, C.Y.,Pan, Y.C.,Wang, Y.L.,Toh, S.I. (deposition date: 2021-06-03, release date: 2022-05-11, Last modification date: 2023-11-29)
Primary citation	Pan, Y.C.,Wang, Y.L.,Toh, S.I.,Hsu, N.S.,Lin, K.H.,Xu, Z.,Huang, S.C.,Wu, T.K.,Li, T.L.,Chang, C.Y. Dual-Mechanism Confers Self-Resistance to the Antituberculosis Antibiotic Capreomycin. Acs Chem.Biol., 17:138-146, 2022 Cited by PubMed: 34994196 DOI: 10.1021/acschembio.1c00799 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.14 Å)

Structure validation