7EON

Crystal structure of the Pepper aptamer in complex with HBC514

Summary for 7EON

• Entry DOI: 10.2210/pdb7eon/pdb
• Descriptor: Pepper (49-MER), GUANOSINE-5'-TRIPHOSPHATE, 4-[(~{Z})-1-cyano-2-[4-[2-(dimethylamino)ethyl-methyl-amino]phenyl]ethenyl]benzenecarbonitrile, ... (5 entities in total)
• Functional Keywords: fluorescent rna, aptamer, hbc514, rna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 16403.30

Authors

Huang, K.Y.,Ren, A.M. (deposition date: 2021-04-22, release date: 2021-11-24, Last modification date: 2023-11-29)

• Primary citation: Huang, K.,Chen, X.,Li, C.,Song, Q.,Li, H.,Zhu, L.,Yang, Y.,Ren, A.; Structure-based investigation of fluorogenic Pepper aptamer.; Nat.Chem.Biol., 17:1289-1295, 2021; PubMed: 34725509; DOI: 10.1038/s41589-021-00884-6

Experimental method

X-RAY DIFFRACTION (2.3 Å)