7ELC

Structure of monomeric complex of MACV L bound to Z and 3'-vRNA

Summary for 7ELC

• Entry DOI: 10.2210/pdb7elc/pdb
• EMDB information: 31180
• Descriptor: RNA-directed RNA polymerase L, RING finger protein Z, 3'-vRNA promoter, ... (5 entities in total)
• Functional Keywords: machupo virus, polymerase, z protein, replication regulation, viral protein-rna complex, viral protein/rna
• Biological source: Machupo mammarenavirus (MACV); More
• Total number of polymer chains: 3
• Total formula weight: 267462.55

Authors

Xu, X.,Peng, R.,Peng, Q.,Shi, Y. (deposition date: 2021-04-09, release date: 2021-05-05, Last modification date: 2021-07-14)

• Primary citation: Xu, X.,Peng, R.,Peng, Q.,Wang, M.,Xu, Y.,Liu, S.,Tian, X.,Deng, H.,Tong, Y.,Hu, X.,Zhong, J.,Wang, P.,Qi, J.,Gao, G.F.,Shi, Y.; Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.; Nat Microbiol, 6:921-931, 2021; PubMed: 34127846; DOI: 10.1038/s41564-021-00916-w

Experimental method

ELECTRON MICROSCOPY (3.1 Å)