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7EBJ

Apo structure of the mouse Trim66 PHD-Bromo dual domain

Summary for 7EBJ
Entry DOI10.2210/pdb7ebj/pdb
DescriptorTripartite motif-containing protein 66, ZINC ION (3 entities in total)
Functional Keywordshistone binding, phd finger, bromodomain, epigenetics, gene regulation
Biological sourceMus musculus (Mouse)
Total number of polymer chains1
Total formula weight21383.44
Authors
Wang, Z.,Jiang, J. (deposition date: 2021-03-09, release date: 2022-03-09, Last modification date: 2023-11-29)
Primary citationZuo, F.,Jiang, J.,Fu, H.,Yan, K.,Liefke, R.,Zhang, J.,Hong, Y.,Chang, Z.,Liu, N.,Wang, Z.,Xi, Q.
A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells.
Cell Stem Cell, 29:948-961.e6, 2022
Cited by
PubMed: 35659877
DOI: 10.1016/j.stem.2022.05.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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