7EA8
Human SETD2 bound to a nucleosome containing oncohistone mutations
Summary for 7EA8
Entry DOI | 10.2210/pdb7ea8/pdb |
EMDB information | 31040 |
Descriptor | Histone-lysine N-methyltransferase SETD2, Histone H3.3, Histone H4, ... (9 entities in total) |
Functional Keywords | setd2, methyltransferase, nucleosome, h3.3k36m, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 11 |
Total formula weight | 195844.55 |
Authors | |
Primary citation | Liu, Y.,Zhang, Y.,Xue, H.,Cao, M.,Bai, G.,Mu, Z.,Yao, Y.,Sun, S.,Fang, D.,Huang, J. Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations. Cell Discov, 7:32-32, 2021 Cited by PubMed: 33972509DOI: 10.1038/s41421-021-00261-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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