7DTE
SARS-CoV-2 RdRP catalytic complex with T33-1 RNA
Summary for 7DTE
Entry DOI | 10.2210/pdb7dte/pdb |
EMDB information | 30852 |
Descriptor | RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (6 entities in total) |
Functional Keywords | covid-19, sars-cov-2, virus, rdrp, nsp12, nsp7, nsp8, rtc, cryo-em, viral protein, rna polymerase, drug target, antiviral, viral protein-rna complex, viral protein/rna |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 6 |
Total formula weight | 191174.31 |
Authors | |
Primary citation | Wu, J.,Wang, H.,Liu, Q.,Li, R.,Gao, Y.,Fang, X.,Zhong, Y.,Wang, M.,Wang, Q.,Rao, Z.,Gong, P. Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex. Cell Rep, 37:109882-109882, 2021 Cited by PubMed: 34653416DOI: 10.1016/j.celrep.2021.109882 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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