7DRW

Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators

Summary for 7DRW

• Entry DOI: 10.2210/pdb7drw/pdb
• EMDB information: 30828
• Descriptor: Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (16 entities in total)
• Functional Keywords: proteasome, immunoproteasome, bovine spleen, pa28, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 42
• Total formula weight: 1153410.70

Authors

Cong, Y.,Xu, C. (deposition date: 2020-12-29, release date: 2021-01-20, Last modification date: 2024-03-27)

• Primary citation: Chen, J.,Wang, Y.,Xu, C.,Chen, K.,Zhao, Q.,Wang, S.,Yin, Y.,Peng, C.,Ding, Z.,Cong, Y.; Cryo-EM of mammalian PA28 alpha beta-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28 alpha beta.; Nat Commun, 12:739-739, 2021; PubMed: 33531497; DOI: 10.1038/s41467-021-21028-3

Experimental method

ELECTRON MICROSCOPY (4.2 Å)