7DNF
DARPin 63_B7 in complex with V3-IY (MN) crown mimetic
Summary for 7DNF
Entry DOI | 10.2210/pdb7dnf/pdb |
Descriptor | DARPin 63_B7, V3-IY (MN) crown mimetic peptide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | designed ankyrin repeat proteins, protein design, protein engineering, anti-hiv, de novo protein |
Biological source | synthetic construct More |
Total number of polymer chains | 6 |
Total formula weight | 78131.07 |
Authors | Wu, Y.,Plueckthun, A. (deposition date: 2020-12-09, release date: 2021-12-15, Last modification date: 2023-11-29) |
Primary citation | Friedrich, N.,Stiegeler, E.,Glogl, M.,Lemmin, T.,Hansen, S.,Kadelka, C.,Wu, Y.,Ernst, P.,Maliqi, L.,Foulkes, C.,Morin, M.,Eroglu, M.,Liechti, T.,Ivan, B.,Reinberg, T.,Schaefer, J.V.,Karakus, U.,Ursprung, S.,Mann, A.,Rusert, P.,Kouyos, R.D.,Robinson, J.A.,Gunthard, H.F.,Pluckthun, A.,Trkola, A. Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization. Nat Commun, 12:6705-6705, 2021 Cited by PubMed: 34795280DOI: 10.1038/s41467-021-27075-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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