7DIY

Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-exoribonuclease domain

Summary for 7DIY

• Entry DOI: 10.2210/pdb7diy/pdb
• Descriptor: nsp10 protein, nsp14-ExoN protein, ZINC ION, ... (5 entities in total)
• Functional Keywords: exoribonuclease, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 2
• Total formula weight: 48492.29

Authors

Lin, S.,Chen, H.,Chen, Z.M.,Yang, F.L.,Ye, F.,Zheng, Y.,Yang, J.,Lin, X.,Sun, H.L.,Wang, L.L.,Wen, A.,Cao, Y.,Lu, G.W. (deposition date: 2020-11-19, release date: 2021-05-19, Last modification date: 2023-11-29)

• Primary citation: Lin, S.,Chen, H.,Chen, Z.,Yang, F.,Ye, F.,Zheng, Y.,Yang, J.,Lin, X.,Sun, H.,Wang, L.,Wen, A.,Dong, H.,Xiao, Q.,Deng, D.,Cao, Y.,Lu, G.; Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.; Nucleic Acids Res., 49:5382-5392, 2021; PubMed: 33956156; DOI: 10.1093/nar/gkab320

Experimental method

X-RAY DIFFRACTION (2.693 Å)