7DD7

Structure of Calcium-Sensing Receptor in complex with Evocalcet

Summary for 7DD7

Entry DOI	10.2210/pdb7dd7/pdb
EMDB information	30647
Descriptor	Calcium-Sensing Receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	casr, calcium-sensing receptor, evocalcet, membrane protein
Biological source	Gallus gallus (Chicken)
Total number of polymer chains	2
Total formula weight	243122.09
Authors	Wen, T.L.,Yang, X.,Shen, Y.Q. (deposition date: 2020-10-27, release date: 2021-06-16, Last modification date: 2021-06-23)
Primary citation	Wen, T.,Wang, Z.,Chen, X.,Ren, Y.,Lu, X.,Xing, Y.,Lu, J.,Chang, S.,Zhang, X.,Shen, Y.,Yang, X. Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor. Sci Adv, 7:-, 2021 Cited by PubMed: 34088669 DOI: 10.1126/sciadv.abg1483 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation