7D42

Structural basis of tropifexor as a potent and selective agonist for farnesoid X receptor

Summary for 7D42

• Entry DOI: 10.2210/pdb7d42/pdb
• Descriptor: Bile acid receptor, Peptide from Nuclear receptor coactivator 2, Tropifexor (3 entities in total)
• Functional Keywords: farnesoid x receptor, tropifexor, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 31194.58

Authors

Jiang, L.,Chen, Y. (deposition date: 2020-09-22, release date: 2020-12-02, Last modification date: 2023-11-29)

• Primary citation: Jiang, L.,Xiao, D.,Li, Y.,Dai, S.,Qu, L.,Chen, X.,Guo, M.,Wei, H.,Chen, Y.; Structural basis of tropifexor as a potent and selective agonist of farnesoid X receptor.; Biochem.Biophys.Res.Commun., 534:1047-1052, 2021; PubMed: 33121679; DOI: 10.1016/j.bbrc.2020.10.039

Experimental method

X-RAY DIFFRACTION (2.697 Å)