7CYK

Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation

Summary for 7CYK

• Entry DOI: 10.2210/pdb7cyk/pdb
• Related: 6LH1 7CYG
• Descriptor: Transporter, sodium/bile acid symporter family, MERCURY (II) ION (3 entities in total)
• Functional Keywords: bile acid transporter, asbt, ntcp, slc10, transport protein
• Biological source: Yersinia frederiksenii
• Total number of polymer chains: 2
• Total formula weight: 66637.72

Authors

Wang, X.,Lyu, Y.,Ji, Y.,Sun, Z.,Zhou, X. (deposition date: 2020-09-03, release date: 2021-01-13, Last modification date: 2023-11-29)

• Primary citation: Wang, X.,Lyu, Y.,Ji, Y.,Sun, Z.,Zhou, X.; An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.; Acta Crystallogr D Struct Biol, 77:108-116, 2021; PubMed: 33404530; DOI: 10.1107/S205979832001517X

Experimental method

X-RAY DIFFRACTION (2.785 Å)