7CM8
High resolution crystal structure of M92A mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae
Summary for 7CM8
Entry DOI | 10.2210/pdb7cm8/pdb |
Related | 5XCP |
Descriptor | Cysteine synthase, SODIUM ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | cysteine synthase, substrate selection, mutant, competetive allostery, transferase |
Biological source | Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (Haemophilus influenzae Rd KW20) |
Total number of polymer chains | 1 |
Total formula weight | 37351.32 |
Authors | Kaushik, A.,Rahisuddin, R.,Saini, N.,Kumaran, S. (deposition date: 2020-07-25, release date: 2020-08-19, Last modification date: 2023-11-29) |
Primary citation | Kaushik, A.,Rahisuddin, R.,Saini, N.,Singh, R.P.,Kaur, R.,Koul, S.,Kumaran, S. Molecular mechanism of selective substrate engagement and inhibitor disengagement of cysteine synthase. J.Biol.Chem., 296:100041-100041, 2020 Cited by PubMed: 33162395DOI: 10.1074/jbc.RA120.014490 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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