7C0Z

Crystal structure of a dinucleotide-binding protein (Y246A) of ABC transporter endogenously bound to uridylyl-3'-5'-phospho-guanosine (Form II)

Summary for 7C0Z

• Entry DOI: 10.2210/pdb7c0z/pdb
• Descriptor: Sugar ABC transporter, periplasmic sugar-binding protein, [(1S,3R,3aR,6aS)-3-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-5,5-bis(oxidanyl)-1,3,3a,4,6,6a-hexahydrocyclopenta[c]furan-1-yl]methyl [(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-2-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl] hydrogen phosphate, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: c-di-gmp/amp, substrate-binding protein, thermus thermophilus, trna synthesis and/or modification, venus fly-trap mechanism, ugpb, transport protein
• Biological source: Thermus thermophilus HB8
• Total number of polymer chains: 2
• Total formula weight: 90146.39

Authors

Kanaujia, S.P.,Chandravanshi, M.,Samanta, R. (deposition date: 2020-05-01, release date: 2021-03-10, Last modification date: 2023-11-29)

• Primary citation: Chandravanshi, M.,Samanta, R.,Kanaujia, S.P.; Structural and thermodynamic insights into the novel dinucleotide-binding protein of ABC transporter unveils its moonlighting function.; Febs J., 288:4614-4636, 2021; PubMed: 33599038; DOI: 10.1111/febs.15774

Experimental method

X-RAY DIFFRACTION (2.2 Å)