7BW8
Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin
Summary for 7BW8
Entry DOI | 10.2210/pdb7bw8/pdb |
Related | 7BW7 |
EMDB information | 30225 30227 30229 30230 |
Descriptor | Insulin receptor, Insulin fusion (2 entities in total) |
Functional Keywords | human insulin receptor, full-length, ectodomain, insulin, conformation., signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 316609.56 |
Authors | |
Primary citation | Yu, D.,Zhang, X.,Sun, J.,Li, X.,Wu, Z.,Han, X.,Fan, C.,Ma, Y.,Ouyang, Q.,Wang, T. Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report