7BAQ

Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24)

Summary for 7BAQ

• Entry DOI: 10.2210/pdb7baq/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium, ... (4 entities in total)
• Functional Keywords: phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
• Biological source: Cricetulus griseus (Chinese hamster); More
• Total number of polymer chains: 2
• Total formula weight: 43403.63

Authors

Oebbeke, M.,Heine, A.,Klebe, G. (deposition date: 2020-12-16, release date: 2022-01-12, Last modification date: 2024-01-31)

• Primary citation: Oebbeke, M.,Koester, H.,Brass, S.,Gerber, H.-D.,Heine, A.,Klebe, G.; Crystal structure of the cAMP-dependent protein kinase A cocrystallized with a chiral ligand (S- and E-configuration) and PKI (5-24); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.54 Å)