7B6F

GSK3-beta in complex with compound (S)-5c

Summary for 7B6F

• Entry DOI: 10.2210/pdb7b6f/pdb
• Descriptor: Glycogen synthase kinase-3 beta, 3-[(3~{S})-3-[(7-chloranyl-9~{H}-pyrimido[4,5-b]indol-4-yl)-methyl-amino]piperidin-1-yl]propanenitrile, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: kinase inhibitors, structure-based drug design, gsk3-beta inhibitor, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 42374.87

Authors

Tesch, R.,Andreev, S.,Koch, P.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-12-07, release date: 2020-12-16, Last modification date: 2024-01-31)

• Primary citation: Tesch, R.,Andreev, S.,Koch, P.,Knapp, S.,Structural Genomics Consortium (SGC); GSK3-beta in complex with compound (S)-5c; To be published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)