7B4R
Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea
Summary for 7B4R
Entry DOI | 10.2210/pdb7b4r/pdb |
Descriptor | Possible 4'-phosphopantetheinyl transferase, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, COENZYME A, ... (5 entities in total) |
Functional Keywords | mycobacterium abscessus 4'-phosphopantetheinyl transferase complex, transferase, inhibition, amidino-urea |
Biological source | Mycobacteroides abscessus ATCC 19977 |
Total number of polymer chains | 1 |
Total formula weight | 26571.82 |
Authors | Maveyraud, L.,Carivenc, C.,Blanger, C.,Mourey, L. (deposition date: 2020-12-02, release date: 2021-11-10, Last modification date: 2024-01-31) |
Primary citation | Carivenc, C.,Maveyraud, L.,Blanger, C.,Ballereau, S.,Roy-Camille, C.,Nguyen, M.C.,Genisson, Y.,Guilhot, C.,Chalut, C.,Pedelacq, J.D.,Mourey, L. Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds. Sci Rep, 11:18042-18042, 2021 Cited by PubMed: 34508141DOI: 10.1038/s41598-021-97197-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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