7B2L

Structure of the endocytic adaptor complex AENTH

Summary for 7B2L

• Entry DOI: 10.2210/pdb7b2l/pdb
• EMDB information: 11715 11987
• Descriptor: ENTH domain of epsin Ent1, ANTH domain of Sla2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (3 entities in total)
• Functional Keywords: membrane protein, clathrin-mediated endocytosis, adapter protein, sla2, epsin-1, enth, anth, cell adhesion
• Biological source: Saccharomyces cerevisiae S288C; More
• Total number of polymer chains: 16
• Total formula weight: 432031.43

Authors

Klebl, D.P.,Lizarrondo, J.,Sobott, F.,Garcia-Alai, M.,Muench, S.P. (deposition date: 2020-11-27, release date: 2021-05-05, Last modification date: 2021-06-02)

• Primary citation: Lizarrondo, J.,Klebl, D.P.,Niebling, S.,Abella, M.,Schroer, M.A.,Mertens, H.D.T.,Veith, K.,Thuenauer, R.,Svergun, D.I.,Skruzny, M.,Sobott, F.,Muench, S.P.,Garcia-Alai, M.M.; Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis.; Nat Commun, 12:2889-2889, 2021; PubMed: 34001871; DOI: 10.1038/s41467-021-23151-7

Experimental method

ELECTRON MICROSCOPY (3.9 Å)