7AZY

Context-specific inhibition of eukaryotic translation by macrolide antibiotics

This is a non-PDB format compatible entry.

Summary for 7AZY

• Entry DOI: 10.2210/pdb7azy/pdb
• EMDB information: 11951
• Descriptor: 60S ribosomal protein L8-A, 60S ribosomal protein L13-A, 60S ribosomal protein L26-A, ... (44 entities in total)
• Functional Keywords: context-specific inhibition, macrolide antibiotic, ribosome, telithromycin
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 42
• Total formula weight: 1916774.59

Authors

Koller, T.O.,Wilson, D.N. (deposition date: 2020-11-17, release date: 2021-05-19, Last modification date: 2022-05-25)

• Primary citation: Svetlov, M.S.,Koller, T.O.,Meydan, S.,Shankar, V.,Klepacki, D.,Polacek, N.,Guydosh, N.R.,Vazquez-Laslop, N.,Wilson, D.N.,Mankin, A.S.; Context-specific action of macrolide antibiotics on the eukaryotic ribosome.; Nat Commun, 12:2803-2803, 2021; PubMed: 33990576; DOI: 10.1038/s41467-021-23068-1

Experimental method

ELECTRON MICROSCOPY (2.877 Å)