7AQM

ADP-ribosylserine hydrolase ARH3 of Latimeria chalumnae in complex with alpha-1''-O-methyl-ADP-ribose (meADPr)

Summary for 7AQM

Entry DOI	10.2210/pdb7aqm/pdb
Descriptor	ADP-ribosylhydrolase like 2, MAGNESIUM ION, Adenosine 5'-diphosphoric acid beta-[(3beta,4beta-dihydroxy-5beta-methoxytetrahydrofuran-2alpha-yl)methyl] estere, ... (4 entities in total)
Functional Keywords	adp-ribosylserine hydrolase, arh3, latimeria chalumnae, alpha-1''-o-methyl-adp ribose, hydrolase
Biological source	Latimeria chalumnae (West Indian ocean coelacanth)
Total number of polymer chains	2
Total formula weight	77822.94
Authors	Rack, J.G.M.,Zorzini, V.,Ahel, I. (deposition date: 2020-10-22, release date: 2021-06-16, Last modification date: 2024-01-31)
Primary citation	Rack, J.G.M.,Liu, Q.,Zorzini, V.,Voorneveld, J.,Ariza, A.,Honarmand Ebrahimi, K.,Reber, J.M.,Krassnig, S.C.,Ahel, D.,van der Marel, G.A.,Mangerich, A.,McCullagh, J.S.O.,Filippov, D.V.,Ahel, I. Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal. Nat Commun, 12:4581-4581, 2021 Cited by PubMed: 34321462 DOI: 10.1038/s41467-021-24723-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation