7AO0

Crystal structure of CotB2 variant F107A in complex with alendronate

Summary for 7AO0

Entry DOI	10.2210/pdb7ao0/pdb
Related	4OMG 4OMH 6GGI 6GGJ 6GGK 6GGL
Descriptor	Cyclooctat-9-en-7-ol synthase, 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
Functional Keywords	terpene synthase, cyclooctatin, lyase
Biological source	Streptomyces melanosporofaciens
Total number of polymer chains	2
Total formula weight	74568.41
Authors	Dimos, N.,Driller, R.,Loll, B. (deposition date: 2020-10-13, release date: 2020-12-02, Last modification date: 2024-01-31)
Primary citation	Raz, K.,Driller, R.,Dimos, N.,Ringel, M.,Bruck, T.,Loll, B.,Major, D.T. The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol. J.Am.Chem.Soc., 142:21562-21574, 2020 Cited by PubMed: 33289561 DOI: 10.1021/jacs.0c11348 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation