7ALQ

human GCH-GFRP inhibitory complex 7-deaza-GTP bound

Summary for 7ALQ

• Entry DOI: 10.2210/pdb7alq/pdb
• Descriptor: GTP cyclohydrolase 1, GTP cyclohydrolase 1 feedback regulatory protein, ZINC ION, ... (7 entities in total)
• Functional Keywords: gtp cyclohydrolase 1, gtpch1, gtp cyclohydrolase i regulatory protein, gfrp, allosteric regulation, complex, allosteric regulator, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 40
• Total formula weight: 686647.94

Authors

Ebenhoch, R.,Nar, H. (deposition date: 2020-10-07, release date: 2021-10-20, Last modification date: 2024-01-31)

• Primary citation: Ebenhoch, R.,Bauer, M.,Reinert, D.,Kersting, A.,Huber, S.,Schmid, A.,Hinz, I.,Feiler, M.,Muller, K.,Nar, H.; Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP.; J.Struct.Biol., 213:107691-107691, 2021; PubMed: 33387654; DOI: 10.1016/j.jsb.2020.107691

Experimental method

X-RAY DIFFRACTION (2.205 Å)