7AB9
Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-656
Summary for 7AB9
Entry DOI | 10.2210/pdb7ab9/pdb |
Related | 6QGP 6QGU 7A28 7A2F 7A8Q 7A9V 7AAG |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | phosphodiesterase, hydrolase, camp hydrolysis, alternative splicing |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 171850.93 |
Authors | Singh, A.K.,Blaazer, A.R.,Zara, L.,de Esch, I.J.P.,Leurs, R.,Brown, D.G. (deposition date: 2020-09-07, release date: 2021-10-06, Last modification date: 2024-01-31) |
Primary citation | Singh, A.K.,Brown, D.G. hPDE4D2 structure with inhibitor NPD-656 To be published, |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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