7AAV
Human pre-Bact-2 spliceosome core structure
Summary for 7AAV
Entry DOI | 10.2210/pdb7aav/pdb |
EMDB information | 11693 |
Descriptor | 116 kDa U5 small nuclear ribonucleoprotein component, Pre-mRNA-processing-splicing factor 8, Pre-mRNA-splicing factor RBM22, ... (20 entities in total) |
Functional Keywords | complex, spliceosome, catalytic activation, splicing |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 17 |
Total formula weight | 1079064.90 |
Authors | Townsend, C.,Kastner, B.,Leelaram, M.N.,Bertram, K.,Stark, H.,Luehrmann, R. (deposition date: 2020-09-04, release date: 2020-12-09, Last modification date: 2020-12-30) |
Primary citation | Townsend, C.,Leelaram, M.N.,Agafonov, D.E.,Dybkov, O.,Will, C.L.,Bertram, K.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R. Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370:-, 2020 Cited by PubMed: 33243851DOI: 10.1126/science.abc3753 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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