6ZXL

Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement

Summary for 6ZXL

• Entry DOI: 10.2210/pdb6zxl/pdb
• EMDB information: 11524
• Descriptor: Protective antigen, Lethal factor (2 entities in total)
• Functional Keywords: anthrax lethal toxin, fully-loaded pre-pore state, membrane translocase, cytotoxic substrate, toxin
• Biological source: Bacillus anthracis; More
• Total number of polymer chains: 10
• Total formula weight: 881472.14

Authors

Quentin, D.,Antoni, C.,Gatsogiannis, C.,Raunser, S. (deposition date: 2020-07-29, release date: 2020-09-02)

• Primary citation: Antoni, C.,Quentin, D.,Lang, A.E.,Aktories, K.,Gatsogiannis, C.,Raunser, S.; Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.; Plos Pathog., 16:e1008530-e1008530, 2020; PubMed: 32810181; DOI: 10.1371/journal.ppat.1008530

Experimental method

ELECTRON MICROSCOPY (4.2 Å)