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6ZX6

Antiparallel basket-type G-quadruplex DNA structure formed in human Bcl-2 promoter containing 8-oxoG

Summary for 6ZX6
Entry DOI10.2210/pdb6zx6/pdb
NMR InformationBMRB: 34542
Descriptorbcl2ex-oxoG19 (1 entity in total)
Functional Keywordsbcl2, g-quadruplex, oxidative stress, 8-oxo-guanine, promoter, dna
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight7977.10
Authors
Bielskute, S.,Plavec, J.,Podbevsek, P. (deposition date: 2020-07-29, release date: 2021-03-10, Last modification date: 2023-06-14)
Primary citationBielskute, S.,Plavec, J.,Podbevsek, P.
Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter.
Nucleic Acids Res., 49:2346-2356, 2021
Cited by
PubMed: 33638996
DOI: 10.1093/nar/gkab057
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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