6ZUF

Urea-based Foldamer Inhibitor chimera C2 in complex with ASF1 Histone chaperone

Summary for 6ZUF

Entry DOI	10.2210/pdb6zuf/pdb
Descriptor	Histone chaperone ASF1A, C2 foldamer/peptide hybrid inhibitor of histone chaperone ASF1, GLYCEROL, ... (5 entities in total)
Functional Keywords	histone chaperone rational design peptidomimetics foldamers, chaperone
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	39664.33
Authors	Bakail, M.,Mbianda, J.,Perrin, E.M.,Guerois, R.,Legrand, P.,Traore, S.,Douat, C.,Guichard, G.,Ochsenbein, F. (deposition date: 2020-07-22, release date: 2021-06-09, Last modification date: 2024-01-31)
Primary citation	Mbianda, J.,Bakail, M.,Andre, C.,Moal, G.,Perrin, M.E.,Pinna, G.,Guerois, R.,Becher, F.,Legrand, P.,Traore, S.,Douat, C.,Guichard, G.,Ochsenbein, F. Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity. Sci Adv, 7:-, 2021 Cited by PubMed: 33741589 DOI: 10.1126/sciadv.abd9153 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.798 Å)

Structure validation