6ZQS
Crystal structure of double-phosphorylated p38alpha with ATF2(83-102)
Summary for 6ZQS
Entry DOI | 10.2210/pdb6zqs/pdb |
Descriptor | Mitogen-activated protein kinase 14, Cyclic AMP-dependent transcription factor ATF-2, 2-[(2,4-difluorophenyl)amino]-7-{[(2R)-2,3-dihydroxypropyl]oxy}-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one, ... (4 entities in total) |
Functional Keywords | transcription, mapk signaling pathways |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 44374.17 |
Authors | Kirsch, K.,Sok, P.,Poti, A.L.,Remenyi, A. (deposition date: 2020-07-10, release date: 2020-11-18, Last modification date: 2024-01-31) |
Primary citation | Kirsch, K.,Zeke, A.,Toke, O.,Sok, P.,Sethi, A.,Sebo, A.,Kumar, G.S.,Egri, P.,Poti, A.L.,Gooley, P.,Peti, W.,Bento, I.,Alexa, A.,Remenyi, A. Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38. Nat Commun, 11:5769-5769, 2020 Cited by PubMed: 33188182DOI: 10.1038/s41467-020-19582-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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