6ZPU

Crystal structure of Angiotensin-1 converting enzyme C-domain with inserted symmetry molecule C-terminus.

Summary for 6ZPU

• Entry DOI: 10.2210/pdb6zpu/pdb
• Descriptor: Angiotensin-converting enzyme, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: angiotensin-1 converting enzyme, c-terminus insertion, metalloprotease, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 71293.33

Authors

Cozier, G.E.,Acharya, K.R. (deposition date: 2020-07-09, release date: 2020-10-28, Last modification date: 2024-01-31)

• Primary citation: Cozier, G.E.,Lubbe, L.,Sturrock, E.D.,Acharya, K.R.; Angiotensin-converting enzyme open for business: structural insights into the subdomain dynamics.; Febs J., 288:2238-2256, 2021; PubMed: 33067882; DOI: 10.1111/febs.15601

Experimental method

X-RAY DIFFRACTION (2 Å)