6ZJE

Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor Ap5A

Summary for 6ZJE

Entry DOI	10.2210/pdb6zje/pdb
Descriptor	GTP:AMP phosphotransferase AK3, mitochondrial, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	gtp:amp phosphotransferase, ap5a, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	26633.96
Authors	Grundstrom, C.,Rogne, P.,Wolf-Watz, M.,Sauer-Eriksson, A.E. (deposition date: 2020-06-28, release date: 2020-09-16, Last modification date: 2024-01-31)
Primary citation	Rogne, P.,Dulko-Smith, B.,Goodman, J.,Rosselin, M.,Grundstrom, C.,Hedberg, C.,Nam, K.,Sauer-Eriksson, A.E.,Wolf-Watz, M. Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3. Biochemistry, 59:3570-3581, 2020 Cited by PubMed: 32822537 DOI: 10.1021/acs.biochem.0c00549 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation