6Z6Z

Crystal structure of an Anticalin directed towards colchicine without ligand

Summary for 6Z6Z

• Entry DOI: 10.2210/pdb6z6z/pdb
• Related: 5NKN
• Descriptor: Neutrophil gelatinase-associated lipocalin, CALCIUM ION (3 entities in total)
• Functional Keywords: anticalin, beta-barrel, colchicine, conformation change, induced fit, lcn2, lipocalin, ngal, protein engineering, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 21535.48

Authors

Skerra, A.,Eichinger, A. (deposition date: 2020-05-29, release date: 2021-06-09, Last modification date: 2024-01-24)

• Primary citation: Ilyukhina, E.,Eichinger, A.,Skerra, A.; Structural rearrangement in the ligand pocket of Colchicalin upon Colchicine binding; To be published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)