6Z5B
Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003128
Summary for 6Z5B
Entry DOI | 10.2210/pdb6z5b/pdb |
Descriptor | Serine/threonine-protein kinase haspin, DIMETHYL SULFOXIDE, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... (4 entities in total) |
Functional Keywords | kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41322.27 |
Authors | Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24) |
Primary citation | Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003128 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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