6YCL

Crystal structure of GcoA T296G bound to p-vanillin

Summary for 6YCL

Entry DOI	10.2210/pdb6ycl/pdb
Descriptor	Aromatic O-demethylase, cytochrome P450 subunit, 4-hydroxy-3-methoxybenzaldehyde, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	aromatic catabolism, cytochrome p450, lignin valorization, protein engineering, oxidoreductase
Biological source	Amycolatopsis sp. (strain ATCC 39116 / 75iv2)
Total number of polymer chains	1
Total formula weight	46177.36
Authors	Hinchen, D.J.,Mallinson, S.J.B.,Allen, M.D.,Ellis, E.S.,Beckham, G.T.,DuBois, J.L.,McGeehan, J.E. (deposition date: 2020-03-18, release date: 2021-02-17, Last modification date: 2024-01-24)
Primary citation	Ellis, E.S.,Hinchen, D.J.,Bleem, A.,Bu, L.,Mallinson, S.J.B.,Allen, M.D.,Streit, B.R.,Machovina, M.M.,Doolin, Q.V.,Michener, W.E.,Johnson, C.W.,Knott, B.C.,Beckham, G.T.,McGeehan, J.E.,DuBois, J.L. Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes. Jacs Au, 1:252-261, 2021 Cited by PubMed: 34467290 DOI: 10.1021/jacsau.0c00103 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation