Summary for 6Y6X
Entry DOI | 10.2210/pdb6y6x/pdb |
EMDB information | 10709 |
Descriptor | 28S ribosomal RNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (49 entities in total) |
Functional Keywords | translation inhibitor, antibiotic |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 46 |
Total formula weight | 2522979.29 |
Authors | Buschauer, R.,Cheng, J.,Berninghausen, O.,Beckmann, R.,Wilson, D.N. (deposition date: 2020-02-27, release date: 2020-07-08, Last modification date: 2023-11-08) |
Primary citation | Osterman, I.A.,Wieland, M.,Maviza, T.P.,Lashkevich, K.A.,Lukianov, D.A.,Komarova, E.S.,Zakalyukina, Y.V.,Buschauer, R.,Shiriaev, D.I.,Leyn, S.A.,Zlamal, J.E.,Biryukov, M.V.,Skvortsov, D.A.,Tashlitsky, V.N.,Polshakov, V.I.,Cheng, J.,Polikanov, Y.S.,Bogdanov, A.A.,Osterman, A.L.,Dmitriev, S.E.,Beckmann, R.,Dontsova, O.A.,Wilson, D.N.,Sergiev, P.V. Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel. Nat.Chem.Biol., 16:1071-1077, 2020 Cited by PubMed: 32601485DOI: 10.1038/s41589-020-0578-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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