6Y2V
Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Summary for 6Y2V
| Entry DOI | 10.2210/pdb6y2v/pdb |
| Descriptor | Low molecular weight phosphotyrosine protein phosphatase, TRIETHYLENE GLYCOL, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | engineered, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 18306.60 |
| Authors | Levy, C. (deposition date: 2020-02-17, release date: 2020-07-22, Last modification date: 2024-01-24) |
| Primary citation | Egbe, E.,Levy, C.W.,Tabernero, L. Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme. Plos One, 15:e0235133-e0235133, 2020 Cited by PubMed: 32584877DOI: 10.1371/journal.pone.0235133 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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