6Y1A

Amyloid fibril structure of islet amyloid polypeptide

Summary for 6Y1A

Entry DOI	10.2210/pdb6y1a/pdb
EMDB information	10669
Descriptor	Islet amyloid polypeptide, AMINO GROUP (2 entities in total)
Functional Keywords	amylin, iapp, amyloid fibril, diabetes, hormone
Biological source	Homo sapiens (Human)
Total number of polymer chains	16
Total formula weight	62805.23
Authors	Roeder, C.,Kupreichyk, T.,Gremer, L.,Schaefer, L.U.,Pothula, K.R.,Ravelli, R.B.G.,Willbold, D.,Hoyer, W.,Schroder, G.F. (deposition date: 2020-02-11, release date: 2020-03-04, Last modification date: 2020-07-22)
Primary citation	Roder, C.,Kupreichyk, T.,Gremer, L.,Schafer, L.U.,Pothula, K.R.,Ravelli, R.B.G.,Willbold, D.,Hoyer, W.,Schroder, G.F. Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-beta fibrils. Nat.Struct.Mol.Biol., 27:660-667, 2020 Cited by PubMed: 32541895 DOI: 10.1038/s41594-020-0442-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation