6XKA
TPX2 residues 7-20 fused to Aurora A residues 116-389 dephosphorylated, and CoAlated on C290
Summary for 6XKA
| Entry DOI | 10.2210/pdb6xka/pdb |
| Related | 6VPG 6VPH 6VPI 6VPJ 6VPL 6VPM |
| Descriptor | TPX2 fragment - Aurora A kinase domain fusion, COENZYME A (3 entities in total) |
| Functional Keywords | ser/thr kinase, transferase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 34674.29 |
| Authors | Lim, D.C.,Yaffe, M.B. (deposition date: 2020-06-26, release date: 2020-08-05, Last modification date: 2023-10-18) |
| Primary citation | Lim, D.C.,Joukov, V.,Rettenmaier, T.J.,Kumagai, A.,Dunphy, W.G.,Wells, J.A.,Yaffe, M.B. Redox priming promotes Aurora A activation during mitosis. Sci.Signal., 13:-, 2020 Cited by PubMed: 32694171DOI: 10.1126/scisignal.abb6707 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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