6XHU

Room temperature X-ray crystallography reveals oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: Insights for enzyme mechanism and drug design

Summary for 6XHU

Entry DOI	10.2210/pdb6xhu/pdb
Descriptor	3C-like proteinase (2 entities in total)
Functional Keywords	sars-cov2 main protease, viral protein, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	2
Total formula weight	67651.09
Authors	Kneller, D.W.,Coates, L.,Kovalevsky, A. (deposition date: 2020-06-19, release date: 2020-07-01, Last modification date: 2023-10-18)
Primary citation	Kneller, D.W.,Phillips, G.,O'Neill, H.M.,Tan, K.,Joachimiak, A.,Coates, L.,Kovalevsky, A. Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M pro : insights into enzyme mechanism and drug design. Iucrj, 7:-, 2020 Cited by PubMed: 33063790 DOI: 10.1107/S2052252520012634 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation