6XH5

Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks

Summary for 6XH5

• Entry DOI: 10.2210/pdb6xh5/pdb
• Descriptor: helical fusion design (2 entities in total)
• Functional Keywords: helical fusion, de novo design, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 6
• Total formula weight: 234719.74

Authors

Bera, A.K.,Hsia, Y.,Kang, A.S.,Baker, D. (deposition date: 2020-06-18, release date: 2021-06-02, Last modification date: 2024-04-03)

• Primary citation: Hsia, Y.,Mout, R.,Sheffler, W.,Edman, N.I.,Vulovic, I.,Park, Y.J.,Redler, R.L.,Bick, M.J.,Bera, A.K.,Courbet, A.,Kang, A.,Brunette, T.J.,Nattermann, U.,Tsai, E.,Saleem, A.,Chow, C.M.,Ekiert, D.,Bhabha, G.,Veesler, D.,Baker, D.; Design of multi-scale protein complexes by hierarchical building block fusion.; Nat Commun, 12:2294-2294, 2021; PubMed: 33863889; DOI: 10.1038/s41467-021-22276-z

Experimental method

X-RAY DIFFRACTION (3.32 Å)