6XEU
CryoEM structure of GIRK2PIP2* - G protein-gated inwardly rectifying potassium channel GIRK2 with PIP2
Summary for 6XEU
| Entry DOI | 10.2210/pdb6xeu/pdb |
| EMDB information | 22150 22151 22152 22153 22154 22155 |
| Descriptor | G protein-activated inward rectifier potassium channel 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, POTASSIUM ION, ... (4 entities in total) |
| Functional Keywords | girk, inwardly rectifying potassium channel, cholesterol, lipids, pip2, transport protein |
| Biological source | Mus musculus (Mouse) |
| Total number of polymer chains | 4 |
| Total formula weight | 159638.84 |
| Authors | Mathiharan, Y.K.,Glaaser, I.W.,Skiniotis, G.,Slesinger, P.A. (deposition date: 2020-06-13, release date: 2021-09-01) |
| Primary citation | Mathiharan, Y.K.,Glaaser, I.W.,Zhao, Y.,Robertson, M.J.,Skiniotis, G.,Slesinger, P.A. Structural insights into GIRK2 channel modulation by cholesterol and PIP2 Cell Rep, 36:109619-, 2021 Cited by DOI: 10.1016/j.celrep.2021.109619PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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