6XAI

Crystal structure of NzeB in complex with cyclo-(L-Trp-L-Pro)

Summary for 6XAI

Entry DOI	10.2210/pdb6xai/pdb
Descriptor	NzeB, PROTOPORPHYRIN IX CONTAINING FE, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, ... (5 entities in total)
Functional Keywords	monooxygenase, dimerase, p450, oxidoreductase
Biological source	Streptomyces sp. NRRL F-5053
Total number of polymer chains	2
Total formula weight	90285.54
Authors	Shende, V.V.,Khatri, Y.,Newmister, S.A.,Sanders, J.N.,Lindovska, P.,Yu, F.,Doyon, T.J.,Kim, J.,Movassaghi, M.,Houk, K.N.,Sherman, D.H. (deposition date: 2020-06-04, release date: 2021-06-09, Last modification date: 2024-04-03)
Primary citation	Shende, V.V.,Khatri, Y.,Newmister, S.A.,Sanders, J.N.,Lindovska, P.,Yu, F.,Doyon, T.J.,Kim, J.,Houk, K.N.,Movassaghi, M.,Sherman, D.H. Structure and Function of NzeB, a Versatile C-C and C-N Bond-Forming Diketopiperazine Dimerase. J.Am.Chem.Soc., 142:17413-17424, 2020 Cited by PubMed: 32786740 DOI: 10.1021/jacs.0c06312 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.489 Å)

Structure validation