6XAH

Structure of a Stable Interstrand DNA Crosslink Involving an dA Amino Group and an Abasic Site

Summary for 6XAH

• Entry DOI: 10.2210/pdb6xah/pdb
• NMR Information: BMRB: 30759
• Descriptor: DNA (5'-D(*TP*AP*TP*GP*TP*CP*TP*AP*AP*GP*TP*TP*CP*AP*TP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*AP*TP*GP*AP*AP*CP*(AAB)P*TP*AP*GP*AP*CP*AP*TP*A)-3') (2 entities in total)
• Functional Keywords: interstrand crosslink, ap site, dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 10920.12

Authors

Kellum Jr., A.H.,Qiu, D.,Voehler, M.W.,Martin, W.J.,Gates, K.S.,Stone, M.P. (deposition date: 2020-06-04, release date: 2021-05-05, Last modification date: 2024-05-01)

• Primary citation: Kellum Jr., A.H.,Qiu, D.Y.,Voehler, M.W.,Martin, W.,Gates, K.S.,Stone, M.P.; Structure of a Stable Interstrand DNA Cross-Link Involving a beta- N -Glycosyl Linkage Between an N 6 -dA Amino Group and an Abasic Site.; Biochemistry, 60:41-52, 2021; PubMed: 33382597; DOI: 10.1021/acs.biochem.0c00596

Experimental method

SOLUTION NMR