6X3I

NNAS Fc mutant

Summary for 6X3I

• Entry DOI: 10.2210/pdb6x3i/pdb
• Descriptor: Immunoglobulin gamma-1 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose, ... (4 entities in total)
• Functional Keywords: antibody fc, glycan engineering, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 25622.89

Authors

Wei, R.,Zhou, Y.F. (deposition date: 2020-05-21, release date: 2020-09-23, Last modification date: 2023-10-18)

• Primary citation: Zhou, Q.,Jaworski, J.,Zhou, Y.,Valente, D.,Cotton, J.,Honey, D.,Boudanova, E.,Beninga, J.,Rao, E.,Wei, R.,Mauriac, C.,Pan, C.,Park, A.,Qiu, H.; Engineered Fc-glycosylation switch to eliminate antibody effector function.; Mabs, 12:1814583-1814583, 2020; PubMed: 32892677; DOI: 10.1080/19420862.2020.1814583

Experimental method

X-RAY DIFFRACTION (2.268 Å)